Male hypogonadism refers to a condition in which the body can’t produce adequate amounts of the hormone that plays a significant role in masculine growth and development during puberty (testosterone) or adequate sperm or both.

You may be born with hypogonadism or can also develop the condition later in life, usually due to an injury or an infection. The effects and treatment rely on the cause and the point in your life when you get it. In most cases, testosterone replacement therapies are effective in relieving the symptoms of male hypogonadism.

Other names for Male Hypogonadism

  • Testosterone deficiency
  • Testosterone deficiency Syndrome
  • Primary hypogonadism
  • Secondary hypogonadism
  • Hypogonadotropic hypogonadism
  • Hypogonadotropic hypogonadism

What Causes Male Hypogonadism?

With growing age, the levels of testosterone hormone in males tend to decrease. This natural decline in testosterone begins after the age of 30 and continues. (at about 1% per year) throughout their lifespan. There are many possible causes of male hypogonadism, such as:

  • Injury or infection of the testes (orchitis)
  • Metabolic disorders including hemochromatosis (very high levels of iron in the body)
  • Chemotherapy for cancer
  • Medications, such as hormones used to treat prostate cancer, opioids, and steroids (such as prednisone)
  • Dysfunction or tumors of the pituitary gland
  • Chronic renal (kidney) failure
  • Alcohol abuse
  • Kallman syndrome
  • Klinefelter syndrome
  • Obesity or extreme weight loss
  • Acute or chronic illness
  • Cirrhosis of the liver
  • Obstructive sleep apnea
  • Uncontrolled type 2 diabetes mellitus
  • High levels of the milk-producing hormone prolactin
  • Inflammatory conditions including sarcoidosis (a condition that leads to inflammation of the lungs and other organs)
  • Congenital defect
  • Previous anabolic steroid abuse
  • Aging
  • Trauma (head injury)
  • Radiation exposure or prior surgery of the brain
  • Estrogen excess (generally from an external or environmental source)
  • Pubertal delay

What Are The Symptoms Of Male Hypogonadism?

Low levels of testosterone can cause several symptoms, which depends on:

  • The age of onset
  • The degree of testosterone deficiency
  • The time for which the loss has been occurring

Adolescents or young males who haven’t yet completed their puberty seem to appear younger than their chronological age. They may have a lack of facial hair, smaller genitalia, failure of the voice to deepen, and difficulty gaining muscle mass even with workouts.

Puberty-onset male hypogonadism can cause:

  • Enlarged breast
  • Decreased testicular size
  • Impaired sexual development

Adult-onset male hypogonadism can cause:

  • Depressed mood
  • Low sperm count
  • Decrease libido
  • Erectile dysfunction
  • Sleep disturbances
  • Lethargy
  • Poor concentration
  • Sweating
  • Hot flashes
  • Breast discomfort and enlargement
  • Decreased muscle mass and strength
  • Osteoporosis and decreased bone mineral density
  • Increased body fat

How Is Male Hypogonadism Diagnosed?

Early diagnosis in boys can help prevent delayed puberty. Early diagnosis and treatment in men help prevent osteoporosis and other health conditions.

Your healthcare provider will take your physical exam to check for your sexual development, including the size of your breasts and testes, pubic hair, and muscle mass. Then, the doctor will check your testosterone levels in the blood to identify if you’ve signs of hypogonadism. As testosterone levels differ, and they are highest in the morning hours, the blood test is generally conducted early in the morning and possibly on more than one day.

If these tests confirm you’ve low testosterone, other tests may be conducted to determine if pituitary abnormality or testicular disorder is the underlying cause. These tests include:

  • Pituitary imaging
  • Semen analysis
  • Genetic testing
  • Testicular biopsy
  • Hormone testing

How Is Male Hypogonadism Treated?

Male hypogonadism is usually treated with testosterone replacement therapy to restore normal testosterone levels. Testosterone can help treat the signs and symptoms of male hypogonadism, including reduced sexual desire, decreased facial and body hair, decreased energy, loss of bone density, muscle mass, etc.

For older men who have symptoms of hypogonadism due to aging, the effectiveness of testosterone replacement therapy isn’t clear.

While you are taking testosterone, your doctor will check the treatment effectiveness and side effects many times during the first year of treatment and annually after that.

There are various types of testosterone replacement therapy, including:

  • Gel
  • Injection
  • Nasal
  • Implantable pellets
  • Patch
  • Buccal cavity

There are various types of gels available on the market for male hypogonadism caused by low testosterone. The one we recommend is Cernos Gel – 1%w/w 5gm, which is prescribed only for men with known health conditions. It helps return to normal testosterone levels effectively.

Cernos Gel – 1%w/w 5gm is recommended for external use only. It is available in different strengths and substitutes; consult your doctor to determine which one you should take and for what duration.

You should apply Cernos Gel – 1%w/w 5gm on your arms and shoulder once a day at almost the same time each day. It needs to be used in the same way as recommended by your doctor. Don’t use Cernos Gel – 1%w/w 5gm too often, and avoid applying it to the genital area. You should wear your clothes immediately after the applied gel area gets dried completely. Do not rinse the site for several hours after the gel application to make sure that the gel is entirely absorbed into the skin.

Cernos Gel – 1%w/w 5gm can sometimes lead to certain side effects, including acne and application site reactions (itching, burning, redness, irritation, etc.)Inform your doctor immediately if these side effects bother you or worsen with time. There might be some effective ways to reduce or prevent them from worsening. Certain side effects such as low sperm count, shortness of breath, and frequent or persistent erections, implies that you should stop using the medication.

Before using Cernos Gel – 1%w/w 5gm, you should share your complete health records with your healthcare provider. Inform your healthcare specialist if you have ever had a stroke, heart attack, or high blood pressure. Your healthcare provider should also know about all other medications you are taking as several medications are known to make Cernos Gel – 1%w/w 5gm less effective or alter the way it works. Your healthcare provider may conduct regular blood tests to keep records of testosterone and PSA (prostate-specific antigen) levels.

How To Buy Cernos Gel – 1%w/w 5gm?

Cernos Gel – 1%w/w 5gm is a common testosterone replacement medication that you can obtain easily from any physical or online pharmacy, depending upon your preferences.

If you are looking for a safe and legitimate online pharmacy to buy Cernos Gel – 1%w/w 5gm, check Cheap Medicine Shop. This pharmacy is licensed and always offers quality medications at reasonable rates.


Male hypogonadism is a common condition that occurs due to low levels of testosterone. Check the symptoms listed in the blog to determine if you have the condition. There are various treatment alternatives available for male hypogonadism. Consult your doctor to know which testosterone replacement therapy would be suitable for you. You can also know more generic medicines in USA .