Sepsis remains the 9th leading cause of disease-related death and the primary cause of infection-related death in the ICU. Sepsis is a devastating disease that results in over 250,000 deaths and 1.3 million hospitalizations per year. In February 2016, the Third International Consensus on Sepsis published Sepsis 3.0, the first new sepsis guidelines since 2003. The new guidelines were welcomed by many since the long interval time since Sepsis 2.0, but have already created a firestorm of controversy especially in emergency medicine. Much of this controversy is due to the move away from the systemic inflammatory response syndrome (SIRS) criteria in favor of the sequential organ failure assessment score (SOFA) and qSOFA scores. I encourage everyone to read the three excellent articles published by the Sepsis 3.0 consensus group in the Journal of the American Medical Association (JAMA). My go-to sepsis apps remain ESCAVO Sepsis, Smart Intern Sepsis, and Sepsis Timer.

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